The microstructures of cryogenically ball-milled Cu were investigated by high-resolution electron microscopy. It was found that the grain-size reduction is a dislocation-controlled continuous process which consists of the formation of small-angle grain boundaries , a gradual increase in misorientations as a result of accumulation of more dislocations and, finally, the formation of large-angle GBs. The GBs were generally curved, wavy or faceted, and heavily strained, which are typical characteristics of nanostructured materials. In addition, extrinsic dislocations were found in many GBs, (...) indicating that most are in a high-energy non-equilibrium configuration, which is consistent with observations in equal-channel angular pressing processed Cu, Ni, and Al-Mg, repetitive corrugation and straightening processed Cu and room-temperature ball-milled Cu. These results support a still-disputed concept that GBs in nanostructured metals processed by severe plastic deformation are mostly in non-equilibrium states. (shrink)

Importance Informed consent is essential to ethical, rigorous research and is important to recruitment and retention in cancer trials.Objective To examine cancer clinical trial (CCT) participants’ perceptions of informed consent processes and variations in perceptions by cancer type.Design and Setting and Participants Cross-sectional survey from mixed-methods study at National Cancer Institute–designated Northeast comprehensive cancer center. Open-ended and forced-choice items addressed: (1) enrollment and informed consent experiences and (2) decision-making processes, including risk-benefit assessment. Eligibility: CCT participant with gastro-intestinal or genitourinary, hematologic-lymphatic (...) malignancies, lung cancer, and breast or gynecological cancer (N = 334).Main Outcome Measures Percentages satisfied with consent process and information provided; and assessing participation’s perceptions of risks/benefits. Multivariable logistic or ordinal regression examined differences by cancer type.Results Most patient-participants felt well informed by the consent process (more than 90% overall and by cancer type) and. most (87.4%) reported that the consent form provided all the information they wanted, although nearly half (44.8%) reported that they read the form somewhat carefully or less. More than half (57.9%) said that talking to research staff (i.e., the consent process) had a greater impact on participation decisions than reading the consent form (2.1%). A third (31.1%) were very sure of joining in research studies before the informed consent process (almost half of lung cancer patients did—47.1%). Most patients personally assessed the risks and benefits before consenting. However, trust in physicians played an important role in the decision to enroll in CCT.Conclusions and Relevance Cancer patients rely less on written features of the informed consent process than on information obtained from the research staff and their own physicians. Research should focus on information and communication strategies that support informed consent from referring physicians, researchers, and others to improve patient risk-benefit assessment and decision-making. (shrink)

The notion of an object file figures prominently in recent work in philosophy and cognitive science. Object files play a role in theories of singular reference, object individuation, perceptual memory, and the development of cognitive capacities. However, the philosophical literature lacks a detailed, empirically informed theory of object files. In this paper, we articulate and defend the multiple-slots view, which specifies both the format and architecture of object files. We argue that object files represent in a non-iconic, propositional format that (...) incorporates discrete symbols for separate features. Moreover, we argue that features of separate categories are stored in separate memory slots within an object file. We supplement this view with a computational framework that characterizes how information about objects is stored and retrieved. (shrink)

There is currently intense interest in the question of the source of our presumed knowledge of truths concerning what is, or is not, metaphysically possible or necessary. Some philosophers locate this source in our capacities to conceive or imagine various actual or non-actual states of affairs, but this approach is open to certain familiar and seemingly powerful objections. A different and ostensibly more promising approach has been developed by Timothy Williamson, according to which our capacity for modal knowledge is just (...) an extension, or by-product, of our general capacity to acquire knowledge of true counterfactual conditionals — a capacity that we deploy ubiquitously in everyday life. Williamson’s account crucially involves a thesis to the effect that modal truths can be explained in terms of counterfactual truths. In this paper, I query Williamson’s account on a number of points, including this thesis. My positive proposal, which owes a debt to the work of Kit Fine on modality and essence, appeals instead to our capacity to grasp essences, understood in a neo-Aristotelian fashion, according to which essences are expressed by ‘real definitions’. (shrink)

When we perceive an object, we perceive the object from a perspective. As a consequence of the perspectival nature of perception, when we perceive, say, a circular coin from different angles, there is a respect in which the coin looks circular throughout, but also a respect in which the coin's appearance changes. More generally, perception of shape and size properties has both a constant aspect—an aspect that remains stable across changes in perspective—and a perspectival aspect—an aspect that changes depending on (...) one's perspective on the object. How should we account for the perspectival aspect of spatial perception? We present a framework within which to discuss the perspectival aspect of perception and put forward three desiderata that any account of the perspectival aspect of perception should satisfy. We discuss views on which the perspectival aspect of perception is analyzed in terms of constitutively mind-dependent appearance properties as well as views on which the perspectival aspect of perception is analyzed in terms of representations of mind-independent perspectival properties. (shrink)

The ability to perceive the shapes of things as enduring through changes in how they stimulate our sense organs is vital to our sense of stability in the world. But what sort of capacity is shape constancy, and how is it reflected in perceptual experience? This paper defends a pluralist account of shape constancy: There are multiple kinds of shape constancy centered on geometrical properties at various levels of abstraction, and properties at these various levels feature in the content of (...) perceptual experience, governing patterns of apparent shape similarity. I propose that the varieties of shape constancy are subserved by the syntactic complexity of perceptual shape representations. By assigning discrete constituents to various abstract shape parameters, these representations attune us to the preservation of certain abstract shape properties through changes in more determinate shape properties. Finally, I draw broader lessons concerning the nature and function of perceptual constancy. (shrink)

As thinkers in the market for knowledge and agents aspiring to morally responsible action, we are inevitably subject to luck. This book presents a comprehensive new theory of luck in light of a critical appraisal of the literature's leading accounts, then brings this new theory to bear on issues in the theory of knowledge and philosophy of action.

This article develops a view of shape representation both in visual experience and in subpersonal visual processing. The view is that, in both cases, shape is represented in a ‘layered’ manner: an object is represented as having multiple shape properties, and these properties have varying degrees of abstraction. I argue that this view is supported both by the facts about visual phenomenology and by a large collection of evidence in perceptual psychology. Such evidence is provided by studies of shape discriminability, (...) apparent motion, multiple-object tracking, and structure-from-motion. Recent neuroscientific work has also corroborated this psychophysical evidence. Finally, I draw out implications of the layered view for processes of concept acquisition. 1 Introduction2 Metric Properties andShape Properties3 Metric Views4 Against Metric Views of Visual Shape Experience5 The Visual System Uses Abstract Shape Properties6 Against Metric Views of Visual Shape Representation7 Neural Underpinnings of Abstract Shape Perception8 Implications. (shrink)

Luck looms large in numerous different philosophical subfields. Unfortunately, work focused exclusively on the nature of luck is in short supply on the contemporary analytic scene. In his highly impressive recent book Epistemic Luck, Duncan Pritchard helps rectify this neglect by presenting a partial account of luck that he uses to illuminate various ways luck can figure in cognition. In this paper, I critically evaluate both Pritchard’s account of luck and another account to which Pritchard’s discussion draws our attention—viz., that (...) due to Nicholas Rescher. I also assess some novel analyses of luck that incorporate plausible elements of Pritchard’s and Rescher’s accounts. (shrink)

In this book Jonathan Lowe offers a lucid and wide-ranging introduction to the philosophy of mind. Using a problem-centred approach designed to stimulate as well as instruct, he begins with a general examination of the mind-body problem and moves on to detailed examination of more specific philosophical issues concerning sensation, perception, thought and language, rationality, artificial intelligence, action, personal identity and self-knowledge. His discussion is notably broad in scope, and distinctive in giving equal attention to deep metaphysical questions concerning the (...) mind and to the discoveries and theories of modern scientific psychology. It will be of interest to any reader with a basic grounding in modern philosophy. (shrink)

In this paper, it is argued that metaphysics, conceived as an inquiry into the ultimate nature of mind-independent reality, is a rationally indispensable intellectual discipline, with the a priori science of formal ontology at its heart. It is maintained that formal ontology, properly understood, is not a mere exercise in conceptual analysis, because its primary objective is a normative one, being nothing less than the attempt to grasp adequately the essences of things, both actual and possible, with a view to (...) understanding as far as we can the fundamental structure of reality as a whole. Accordingly, it is urged, the deliverances of formal ontology have a modal and epistemic status akin to those of other a priori sciences, such as mathematics and logic, rather than constituting rivals to the claims of the empirical sciences, such as physics. (shrink)

This chapter contains sections titled: The Syntax and Semantics of Complex Sortal Terms On the Identity of Sorts.

There is a widespread assumption that the classical work in philosophical semantics of Saul Kripke (1980) and Hilary Putnam (1975) has taught us that the essences of natural kinds of substances, such as water and gold, are discoverable only a posteriori by scientific investigation. It is such investigation, thus, that has supposedly revealed to us that it is an essential property of water that it is composed of H2O molecules. This is the way in which Scott Soames, in a recent (...) paper, makes the point in the case of water and H2O: [Here is] how a Kripkean explanation of the necessary a posteriority of [‘Water = H2O’] would go – or at any rate my version of it. The account holds that ‘water’ is a non-descriptive, directly-referential term designating a substance – where substances are taken to be physically constitutive kinds (instances of which share the same basic physical constitution). It is further assumed that a kind of this sort may have different instances in different world-states, and that if a and b are kinds with the same instances in all possible world-states, then a is b. These are clearly metaphysical assumptions, to which we add the natural corollary that for any substance, s, if, in some possible world-state, instances of s have a certain molecular structure, then instances of s have that structure in every world-state. In other words, we assume that it is an essential property of a substance that instances of it have the molecular structure they do. From this it follows that [‘Water = H2O’] is necessary if true, and that ‘H2O’– which I take to be equivalent to ‘the substance instances of which have a molecular structure with two hydrogen atoms and one oxygen atom’– is a rigid designator. Being true, [‘Water = H2O’] is, therefore, necessary. Since knowing the proposition it expresses requires knowing of a certain substance that its instances have a particular chemical structure, [‘Water = H2O’] is knowable only a posteriori. (Soames 2007: 36). (shrink)

‘Water is H2O’ is one of the most frequently cited sentences in analytic philosophy, thanks to the seminal work of Saul Kripke and Hilary Putnam in the 1970s on the semantics of natural kind terms. Both of these philosophers owe an intellectual debt to the empiricist metaphysics of John Locke's Essay Concerning Human Understanding, while disagreeing profoundly with Locke about the reality of natural kinds. Locke employs an intriguing example involving water to support his view that kinds (or ‘species’), such (...) as water and gold, are the workmanship of the human mind. This is the point of his story about a winter visitor to England from Jamaica, who is astonished to find that the water in his basin has turned solid overnight, and proceeds to call it ‘hardened water’. Locke criticizes this judgement, maintaining that it is more consonant with common sense to regard water and ice as different kinds of substance. Putnam, by implication, disagrees. Deploying his imaginary example of Twin Earth—a distant planet where a watery-looking substance, XYZ, rather than H2O, fills the oceans and rivers—he maintains that common sense supports the judgement that XYZ and H2O, despite their superficial similarity, are not the same kind of substance, precisely because their molecular compositions are different. Here it will be argued that both views are mistaken, but that, in this dispute, Locke has more right on his side than his modern opponents do. (shrink)

In this paper, I first of all define various kinds of ontological dependence, motivating these definitions by appeal to examples. My contention is that whenever we need, in metaphysics, to appeal to some notion of existential or identity-dependence, one or other of these definitions will serve our needs adequately, which one depending on the case in hand. Then I respond to some objections to one of these proposed definitions in particular, namely, my definition of (what I call) essential identity-dependence. Finally, (...) I show how a similar approach can be applied in the theory of truthmaking, by offering an account of the truthmaking relation which defines it in terms of a type of essential dependence. I also say why I think that this approach is preferable to one which treats the truthmaking relation as primitive. More generally, my view is that accounts of dependence or ‘grounding’ which treat these notions as primitive are less satisfactory than my own position, which is that in all cases a suitable definition is forthcoming if we look hard enough. (shrink)

ABSTRACTIn a recent article in this journal, Joshua Shepherd presents and rejects a new argument for the sceptical conclusion that everyday decisions aren't intentional actions. After relating his focal argument to a different argument for the same conclusion that is presented and rejected by Alfred Mele, I defend these arguments from extant criticisms, and develop new objections that shed light on the intentionality of typical decisions.

Construing miracles as \textquotedblleft{}violations,\textquotedblright I argue that a law of nature must specify some kind of possibility. But we must have here a sense of possibility for which the ancient rule of logic---ab esse ad posse valet consequentia---does not hold. We already have one example associated with the concept of statute law, a law which specifies what is legally possible but which is not destroyed by a violation. If laws of nature are construed as specifying some analogous sense of what (...) is naturally possible, then they need not be invalidated by a (rare) violation, and Humean miracles remain a genuine possibility. (shrink)

For the good that I would, I do not; but the evil which I would not, that I do. Now if I do that I would not, it is no more I that do it, but sin that dwelleth in me. Romans 7.19-20.

When Kepler concluded that the orbit of Mars was not a circle, he was led to the belief that the orbit was an oval touching the circle at the apsides and lying within the circle at other points. In the definition of the oval, physical hypotheses played a primary role. Two forces were involved; a tractive force arising from the effect of the solar rays rotating with the sun, and a directing force arising from a natural instinct of the planet (...) itself. The former pushed the planet along the orbit while the latter enabled the planet to steer itself across the stream of the solar vortex in a small epicycle. In adopting this physical theory to determine the oval, Kepler was led into what he himself described as ‘a new labyrinth’. After several attempts to construct the oval, and by progressively eliminating the sources of error from his calculating procedures in order to arrive at an accurate mathematical formulation of the physical hypotheses, he was able to conclude that the oval was inconsistent with the empirical data and the physical theory in need of modification. (shrink)

Recently, Terry Horgan and Matjaž Potrč have defended the thesis of ‘existence monism’, according to which the whole cosmos is the only concrete object. Their arguments appeal largely to considerations concerning vagueness. Crucially, they claim that ontological vagueness is impossible, and one key assumption in their defence of this claim is that vagueness always involves ‘sorites-susceptibility’. I aim to challenge both the claim and this assumption. As a consequence, I seek to undermine their defence of existence monism and support a (...) common-sense pluralist ontology of ‘ordinary objects’ as being fully consistent with a thoroughgoing metaphysical realism. (shrink)

'identity' includes a family of relations and is wrongly restricted to what satisfies leibniz's law: diachronic and strict identity are related since the criteria of the former are just the criteria of continuity of stages of the strictly identical continuant. A general account can be given in terms of the preservation of a weighted preponderance of properties of the stages. Puzzle cases arise because of contextual shifts in the weightings assigned; in the case of persons this is particularly clear because (...) of change of emphasis between mental and physical, Both of which classes of predicate are applicable. (shrink)